Sunday, June 12, 2016

PubMed Update May 2016

19 this month. Enjoy!

Tjagvad C, Skurtveit S, Linnet K, Andersen LV, Christoffersen DJ, Clausen T.
Eur Addict Res. 2016 Jun 1;22(5):249-258. [Epub ahead of print]
Comments: Patients on very high doses of methadone or also using benzodiazepines were at higher risk of death.

Salani DA, Zdanowicz M, Joseph L.
J Psychosoc Nurs Ment Health Serv. 2016 Jun 1;54(6):30-7. doi: 10.3928/02793695-20160518-05.
Comments: Epidemiologic review.

Gatewood AK, Van Wert MJ, Andrada AP, Surkan PJ.
Addict Behav. 2016 May 17;61:40-46. doi: 10.1016/j.addbeh.2016.05.013. [Epub ahead of print]
Comments: Qualitative interviews with medical providers.

Elzey MJ, Barden SM, Edwards ES.
Pain Physician. 2016 May;19(4):215-28.
Comments: Non-fatal events are far more common, not well-predicted by risk factors, and in need of additional research.

Doyon S, Benton C, Anderson BA, Baier M, Haas E, Hadley L, Maehr J, Rebbert-Franklin K, Olsen Y, Welsh C.
Am J Addict. 2016 Jun;25(4):301-6. doi: 10.1111/ajad.12384. Epub 2016 May 24.
Comments: Interesting case series of naloxone reversals reported to poison control. They report a 75.6% “response rate” although some of the remainder was “unknown” and was there were only 2 deaths among 78 cases, suggesting a rate closer to 97.5%. Response rate to heroin was higher than for prescription opioids. Of the 43 suspected heroin events, 31 went to the ED, 25 were discharged, and 5 required ICU care. Of 31 suspected prescription opioid 20 went to the ED, 9 were discharged, and 6 required ICU care. This is consistent with the more complicated nature of prescription opioid overdose.

Fisher R, O'Donnell D, Ray B, Rusyniak D.
Prehosp Emerg Care. 2016 May 24:1-6. [Epub ahead of print]
Comments: About a 65% response rate among 117 administrations and 1 combative individual.